A case of mantle cell lymphoma with immune thrombocytopenia detected by abnormal gingival bleeding as a primary symptom

Abstract

Mantle cell lymphoma （MCL） is a rare lymphoma of B-cell origin. We report a case of MCL with immune thrombocytopenia detected by abnormal gingival bleeding as a primary symptom.
A 76-year-old man was referred to our hospital because of gingival bleeding. Gingival bleeding of the anterior maxillary region and purpura of the lower extremity was detected. Because the platelet count was 0.0 × 10⁴/μl ,we suspected blood disorders such as ITP. We referred the patient to a hematologist, and he was hospitalized immediately. He received adrenocortical steroid therapy, and the platelet count returned to the normal range.Because bone marrow puncture showed infiltration of malignant lymphoma cells （MCL）, MCL （Stage IV A） with thrombocytopenia was diagnosed. He received chemotherapy with rituximab-2CdA. After treatment, remission was achieved, and there has been no evidence of recurrence.
Immediate examination and accurate diagnosis are essential in patients who are referred because of oral hemorrhage with a primary symptom of blood disorders.