2011 Volume 57 Issue 8 Pages 476-480
Recently, chronic sclerosing sialadenitis （Küttner’s tumor） has been suggested to be an IgG4-related disease. A 69-year-woman with a painless, bilateral submandibular swelling was referred to our hospital. She was given a diagnosis of Küttner’s tumor in March 2004. We examined a specimen of the submandibular gland by IgG immunostaining. The examination revealed severe infiltration of IgG4-positive plasmacytes. IgG4-related disease was newly diagnosed. Nearly 6 years have passed since the submandibular glands were removed surgically, and the lacrimal glands were bilaterally swollen. We report a case of IgG4-related chronic sclerosing sialadenitis （Küttner’s tumor） with suspected transition to IgG4-related Mikulicz’s disease.
