Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Case reports
A case of amyotrophic lateral sclerosis (ALS) associated with oral symptoms
Nobuyoshi TOMOMATSUNami MACHIDAKoichi NAKAKUKIYutaka SATOMasashi YAMASHIROKiyoshi HARADA
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JOURNAL FREE ACCESS

2014 Volume 60 Issue 3 Pages 142-146

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Abstract
Amyotrophic lateral sclerosis (ALS) is an incurable, progressive, and neurodegenerative disease specifically affecting both upper and lower motor neurons. It induces dysphagia, reduction of respiratory function, and limb muscle weakness, leading to aspiration pneumonia and respiratory insufficiency. ALS can be detected at dental visits on the basis of early oral symptoms such as dysphagia. However, there are few reports describing ALS in dental journals. We describe a man aged 59 years who visited our department because of functional changes, including decreased swallowing ability. Imaging studies demonstrated no tumor lesions, but tongue fasciculations were present. Videofluorographic evaluation revealed incorrect swallowing (aspiration) and food remaining in the larynx. We consulted the department of neurology in our university hospital. Because needle electromyography and other examinations ruled out other possible diseases, the patient was given a diagnosis of ALS. We made a palatal augmentation prosthesis to maintain deglutition function and followed up oral function. Oral symptoms of ALS are sometimes observed in its early stage. Therefore, oral surgeons and dentists need to possess adequate knowledge about this disease.
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© 2014 Japanese Society of Oral and Mxillofacial Surgeons
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