Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Case reports
A case of neurosyphilis with inflammation of the oral mucosa
Miho TAKAHASHITaiki SUZUKIYuji HAMADAKeisuke ONOKazunari KARAKIDAHaruo SAKAMOTO
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2017 Volume 63 Issue 11 Pages 576-581

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Abstract

Syphilis is a sexually transmitted disease caused by a Treponema pallidum infection. We encountered a patient who presented with stomatitis and was given a diagnosis of secondary syphilis. The patient was a 42-year-old woman with chief complaints of difficulty in oral ingestion due to pain in the oral cavity, fever, headache, hair loss, systemic roseola, and keratitis. Serological tests revealed positive results for rapid plasma reagin (RPR) and Treponema pallidum hemagglutination assay (TPHA), forming the basis of our secondary syphilis diagnosis. The bone marrow aspiration test showed positive results for fluorescent treponemal antibody-absorption (FTA-ABS), indicating a neurosyphilis comorbidity. The patient was treated with benzyl penicillin potassium 24 MU/ day for 14 days. Three months after the initiation of treatment, the quantitative value of RPR decreased by 3.7-fold, which indicates cure.

 The recent prevalence of same-sex intercourse and oral sex are causing serious problems because sexually transmitted diseases affect not only sexual organs but also the oropharyngeal tract. The departments that treat sexually transmitted diseases are mainly urology, gynecology, and dermatology. However, there is a concern with regard to an increasing number of cases in which sexually transmitted diseases are diagnosed because of oropharyngeal lesions. Therefore, oral surgeons should also become familiar with the diagnosis and treatment of such diseases.

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© 2017 Japanese Society of Oral and Mxillofacial Surgeons
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