2019 Volume 65 Issue 5 Pages 333-338
Desmoplastic fibroma is a benign fibrous tumor of bone, initially described by Jaffe in 1958. Although classified as benign, it frequently shows local aggressive behavior and has a high rate of recurrence. In this article, we report the spontaneous regression of suspected desmoplastic fibroma in the mandible, which showed recurrence and rapid growth after surgery. An 81-year-old woman visited our department with a chief complaint of swelling of the right buccal mucosa. Radiographic examination showed a lesion suspected to be a solid tumor in the right-side wisdom tooth apical region of the mandible. The lesion was removed by enucleation and curettage with the patient under general anesthesia, and the clinical diagnosis was an odontogenic tumor. Histopathologically, the mass was diagnosed as a suspected desmoplastic fibroma. Radiographic examination showed recurrence and rapid growth of the tumor in the 8th month after surgery. We recommended an extended surgical operation, but she was observed without treatment at her strong request. She has been followed up for 30 months since surgery and the lesion size gradually became smaller. Although the mechanism and cause of the spontaneous regression is difficult to determine, further follow-up is necessary.
