2020 Volume 66 Issue 12 Pages 650-654
Spindle cell lipoma is a rare subtype of lipoma in the oral cavity. Although simple lipoma is easily diagnosed by MRI, it is sometimes difficult to distinguish spindle cell lipoma from liposarcoma due to its similar MRI appearance. A 76-year-old man was referred to our department complaining of a painless mass at the right margin of his tongue. A 10 mm diameter spherical tumor was located under a normal submucosa. MRI revealed a heterogeneous tumorous lesion at the right margin of the tongue in T1- and T2-weighted images. Although lipoma was most highly suspected, liposarcoma was also considered due to the MRI findings. Thus, the tumor was resected with a safety margin. Histopathologically, the tumor possessed a capsule composed of mature adipocytes and spindle cells without muscle tissue. Immunohistochemically, the spindle cells showed S-100 protein-negative and CD34-positive. The lesion was diagnosed as spindle cell lipoma. There has been no recurrence during the 1-year follow-up term.
