A case of primary cardiac intimal sarcoma with distant metastasis of the mandible

Abstract

　A 63-year-old woman with a primary cardiac intimal sarcoma underwent tumor debulking and bioprosthetic valve replacement at the Department of Cardiology of our hospital in November 2020, followed by radiotherapy as additional treatment.
　In September 2021, she was referred to our department for investigation and treatment of a radiolucency in the left mandibular third molar crown that had been identified at a local dental clinic. After further investigation, the left mandibular second and third molars were extracted and a tumor was removed from the mandible, which was diagnosed histopathologically as odontogenic myxoma. Five months postoperatively, a tumorous lesion was identified in the left buccal region, and although it was diagnosed as recurrent odontogenic myxoma when biopsied, retesting yielded a histopathological diagnosis of distant metastasis to the mandible of the intimal sarcoma that had originally arisen in the left atrium. A joint conference with the Department of Cardiovascular Surgery was held to discuss the treatment strategy, and in April 2022 a mandibular tumorectomy was conducted with a view to secondary treatment. However, the patient died from recurrence of the primary tumor one year and two months after this operation.