Intraepithelial carcinoma (carcinoma in situ) in the oral region: Report of two cases

Abstract

An intraepithelial carcinoma (carcinoma in situ) is characterized by marked cellular pleomorphism and by loss of polarity and surface stratification, with the whole thickness of the epithelium showing malignant cellular features. However, the basement membrane is intact.
In this paper, 2 cases of intraepithelial carcinomas in the oral region are presented.
Case 1: A 71-year-old man visited our clinic complaining of a white lesion in the floor of the mouth. The lesion was excised and thin split skin grafting was done under local anesthesia.
Case 2: A 68-year-old woman visited our clinic complaining of a white lesion with erosion in the right margin of the tongue. The lesion was excised under general anesthesia. Afterwards, radiotherapy by Linac and ⁶⁰Co were added.
Pathologic diagnoses of the excised specimens of both patients were intraepithelial carcinomas.
Postoperative course was satisfactory.