New bone formation in the jaw with cancer invasion after pre-operative treatment

Abstract

The effect of the pre-operative therapy on the formation of new bone was examined in ten cases of gingival carcinoma of the mandible. All of the cases was treated with radiotherapy and/or chemotherapy before surgical operation. The effect of the pre-operative therapy was evaluated on the histopathological basis of classification by Oboshi and Shimosato. As a results, the formation of new bone was notably observed in four of ten cases. These four cases were G.III or IV in Oboshi and Shimosato's classification. Such active formation of new bone progressed along the periosteum and aponeurosis.