The immunological parameters in the patient with malignant tumor of head and neck region

Abstract

Concerning 23 patients diagnosed as having head and neck region malignant tumor, we studied PPD, PHA, Su-PS skin reaction, and the change of blood lymphocytes subpopulation using the OK series monoclonal antibody.
Skin reactions showed tendencies of decrease in the following order: good prognostic cases, cancerous cases, and death cases.
In regard to OKT-3+, OKT-4⁺, OKT-4⁺/OKT-8⁺, they showed tendencies of decrease in the following order;good prognostic cases, cancerous cases, and death cases.
We didn't get a significant correlation coefficient from OKT-8⁺, OKIal⁺.
The OKT-4⁺/OKT-8⁺decreased in the case of operation, and irradiation therapy.