1987 Volume 33 Issue 5 Pages 983-990
Virchow observed a unique disorder stained with iodine.He believed that it had a certain similarity to cellulose, and named the material “amyloid”.With the recent progress in delineating the chemical composition of various amyloid proteins, a more exact clinico-immunological classification is now possible.
This is a case of secondary amyloidosis whose chief complaint was submucosal hemorrage and swelling resulted from self-inflicted trauma during mastication. A biopsy taken from the lateral border of the tongue was stained with H. E., PAS and Congo red.The Congo red stained sections were viewed in the polarizing microscope and a unique green birefringence was observed.This is a simple and useful procedure for establishing the presence of amyloid
