Abstract
Solitary neurofibroma of the tongue is very rare. A 60-year-old woman was referred to our clinic with the chief complaint of a tumorous lesion at the midline of her tongue. Under the clinical diagnosis of a fibroma, excisional biopsy was performed. The pathologic findings revealed a picture of a neurofibroma. The tumor cells were positive for S-100 protein and within the tumor were several nerve fibers positive for myelin basic protein by the immunohistochemical method. Neither caf é au lait spots nor other neurofibroma of the skin were noted.
It was diagnosed as a solitary neurofibroma of the tongue, and this is the third case reported in Japanese literature.
