A rare case of syphilis with primary complex in the lip and submaxillary region

Abstract

The patient was a 47-year-old male suffering from mucosal lesion of the upper lip and a submaxillary region swelling. The painless mucosal ulcer was seen with a slightly raised margin and induration in the left side of the upper lip, and a semifist-sized indurated lymphonode with a slight pain was observed in the left submaxillary region. Serological examination revealed the elevation of TPHA-T at a titer of 1: 1, 280 and RPR-T 1: 4. Further, by using Warthin-Starry method, Treponema pallidum could be stained in the biopsy specimen taken from the labial lesion.
This rare case presented a typical syphilitic primary complex that had a hard chancre on the lip and hard buboses of submaxillary lymphonodes.
The patient was treated per us with ANIPC-CVA for six weeks, which was enough to eliminate the syphilic lesions. The blood serological data entered the normal range two months after administration.