1990 Volume 36 Issue 8 Pages 1838-1850
The purpose of this experimental study was to reveal a difference between Cortico-Cancellous Bone Block (CCBB) and Particulate Cancellous Bone and Marrow (PCBM) concerning the bone bridge formation in alveolar clefts. Artificial alveolar clefts were surgically produced in the incisive bone of 39 adult mongrel dogs. The second and third incisor teeth were removed, then bony incomrnunication and an adequate size of bony defect were created. The nasal mucosa was not incised, while the oral mucosa was divided into two at the central part and a gauze tanponade was inserted into the bony defect. Repair of the clefts was made by grafting an autogenous CCBB or PCBM obtained from the iliac crest in 30 dogs. Flaps were advanced over the grafted area and sutured to gain the primary closure. Dogs were followed radiographically for months untill they were killed. Five dogs were killed at time intervals of 1, 3, and 6 months after grafting with CCBB or PCBM.
The other 9 animals were served as controls. These experimental animals were all examined histopathologically and contact microradiographically. The results were as follows: 1) These artificial alveolar clefts were useful for the bone grafting model. 2) Bone bridge formation occurred earlier in PCBM grafts than in CCBB grafts. These differences were probably ascribed to the adaptation to the clefts and the bone modelling patterns employed. 3) Poor adaptation caused a narrow bone bridge due to cortical bone resorption in CCBB grafts. In PCBM grafts, new bone formation was observed all over the transplanted zone with α well shaped bone bridge. 4) A primary closure of the transplanted area and an enough mass of bone semed to be important for making a well shaped bone bridge in PCBM grafts. 5) From these results, PCBM was considered to be a better material for bone grafts in alveolar clefts than CCBB.
