Two cases of oral hairy leukoplakia in HIV-infected patients

Kazumasa SUGIHARA; Kenji ARIMURA; Yasushi IWASHIGE; Kiyomi KAWASHIMA; Akiroh OHKUBO; Sukehide YAMASHITA

doi:10.5794/jjoms.40.170

Kazumasa SUGIHARA, Kenji ARIMURA, Yasushi IWASHIGE, Kiyomi KAWASHIMA, Akiroh OHKUBO, Sukehide YAMASHITA

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Keywords: HIV-infected patient, oral hairy leukoplakia, lateral border of the tongue

JOURNAL FREE ACCESS

1994 Volume 40 Issue 1 Pages 170-172

DOI https://doi.org/10.5794/jjoms.40.170

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Abstract

Oral hairy leukoplakia (OHL) occurs mainly on the lateral border of the tongue of human immunodeficiency virus (HIV)-infected patients. Recent studies have demonstrated Epstein-Barr virus in the epithelial cell of OHL.
We described two cases of OHL which developed in HIV-infected patients with hemophilia. Light microscopic investigation revealed parakeratosis, acanthosis, koilocytosis and lack of inflammation in the subepithelial tissue. Viral particles and nucleocapsids of Epstein-Barr virus were found in the epithelial cells by electron microscopy.

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