1997 Volume 43 Issue 2 Pages 94-96
A number of studies have suggested that histological grading of biopsy specimensof tumors might be a valuable prognostic indicator for oral cancers. This study examined the relationship between the tumor histological grade of biopsy specimens and that of resected specimens obtained from 32 patients with oral squamous cell carcinomas who received no preoperative treatment. Differences between biopsy and resected specimens were found with respect to differentiation in 13 of 32 cases (40.6%), mitosis in 7 /32 (21.9%), nuclear atypism in 6 /32 (18.8%), mode of invasion in 16/32 (50.0%) and lymphocyte infiltration in 3 /32 (9.4%). In tongue carcinoma, the differentiation of the resected specimens was higher than that of the biopsy specimens. In about half of the cases, the mode of invasion of the resected specimens was 1 grade higher than that of the biopsy specimens. This tendency was strongest for cases with an advanced T stage.
