Abstract
Bone grafts are useful for the placement of implants in atrophic bone in edentulous regions. Usually, grafted bone undergoes resorption and provides inadequate support for implants. The guided bone regeneration (GBR) method can prevent resorption of grafted bone; however, GBR has some disadvantages, including exposure of the membrane and infection. Platelet rich plasma (PRP) accelerates wound healing by autologous growth factors. We consider growth factors of PRP to promote sufficient bone for implants. In this study, we used PRP gel to graft, bone harvested from the chin to the anterior maxillary region, which had undergone resorption. After 14 weeks, we decided that there was sufficient bone in the region on computed tomographic examination. After 16 weeks, implants were able to be placed, despite bone resorption. Biopsy of bone specimens revealed active osteogenesis and bone remodeling. Our results suggest that PRP could accelerate bone healing and remodeling, but could not prevent bone resorption in a similar manner to GBR. We confirmed that PRP gel is beneficial at the time of bone grafting for implants.
