Abstract
A case of MALT lymphoma of the hard palate suggesting an association with Sjogren's syndrome (SS) is reported. A 49-year-old woman was referred to the Department of Dentistry and Oral Surgery, Kawaguchi Municipal Medical Center because of a painless swelling in the right side of the hard plate. The mass, measuring 50×30×15mm, was soft and elastic and had a smooth surface. Magnetic resonance imaging demonstrated a well-defined solitary mass in the right side of the hard plate. The pathological diagnosis of the biopsy specimen was marginal zone B-cell lymphoma, extranodal (MALT-type)(REAL classification). Three cycles of CHOP therapy induced complete remission. Then, 3 more cycles of chemotherapy were given. An examination for dry mouth revealed that she met the diagnostic criteria for SS. An association of the MALT lymphoma with SS was strongly suggested. There has been no evidence of recurrence of the lesion as of 1 year after diagnosis.
