Abstract
We describe the first case of oncocytic myoepithelioma in Japan. The patient was a 53-year-old woman who had a painless mass on the hard palate. The tumor was surgically removed under general anesthesia. The tumor was encapsulated by fibrous tissue. Histologically, the tumor was composed mainly of epithelioid round or oval myoepithelial cells with abundant eosinophilic fine granular cytoplasm. Immunohistochemical studies revealed positive reactions for S-100 protein, vimentin, and cytokeratin in the tumor cells. In addition, the cytoplasm was intensely stained with antibody to mitochondrial antigen. A final diagnosis of oncocytic myoepithelioma was made. Two years postoperatively, there is no sign of recurrence.
