Abstract
Leiomyoma is a benign tumor originating from smooth muscle and most frequently arises in the uterus or alimentary tract. Oral leiomyoma is extremely rare because of the paucity of smooth muscle in the oral cavity. We report a case of leiomyoma that developed in the cheek mucosa.
A 44-year-old man presented with a small raised, painless lesion in the mucosa of the left cheek. He had had the lesion for more than 15 years. Leiomyoma was diagnosed on biopsy, the tumor was enucleated under general anesthesia. Histologically, the tumor was composed of spindle cells arranged in interlacing bundles with calcification. The histopathological diagnosis was leiomyoma (non vascular type). This diagnosis was supported by the results of vimentin, α-smooth muscle actin, cytokeratin, and S-100 protein immunostaining. There has been no evidence of recurrence for 38 months after surgery.
