Abstract
A case of synchronous double cancers of the tongue and esophagus in a 57-year-old man is presented. The tongue cancer was histologically diagnosed as squamous cell carcinoma and successfully treated with preoperative radiochemotherapy and repeated operations. Endoscopic examination performed before treatment of the tongue cancer revealed no abnormal features in the esophagus. One month after completion of treatment for the tongue cancer and 3.5 months after initial endscopic examination, an advanced esophageal cancer was detected and histologically diagnosed as carcinosarcoma. He died of uncontrolled esophageal cancer and metastasis. The patient's history, such as heavy smoking, overconsumption of alcohol, preoperative radiochemotherapy, and repeated operations for tongue cancer, suggested that he might be an immunocompromised patient with a high risk of synchronous double primary cancers.
