Abstract
Acinic cell carcinoma usually arises in the parotid gland and rarely occurs in the minor salivary glands. We report a case of acinic cell carcinoma of papillary cystic type arising in the buccal mucosa. The patient was a 45-year-old woman who had a painless swelling in the right buccal mucosa. The tumor measured 18×15mm and was elastic hard in consistency. The tumor was excised under local anesthesia. Histologically, the tumor appeared to be encapsulated, and the tumor cells were arranged in papillary and partially microcystic patterns. Immunohistochemical examination showed that the tumor cells were positive for S-100 protein, lysozyme, α-antit rypsin, and AE1/AE3 and partially positive for periodic acid-Schiff (PAS). The histopathological diagnosis was acinic cell carcinoma of papillary cystic type. The postoperative course was uneventful, and there was no evidence of recurrence or metastasis 20 months after operation.