Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
A case of MALT lymphoma of the buccal mucosa diagnosed by gene analysis
Masahito SHIGEMATSUYoshio YAMASHITAJunta KIDOMitsuhiro TSUJIAtsushi DANJOMasaaki GOTO
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2007 Volume 53 Issue 4 Pages 248-252

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Abstract
Mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) is a low-grade malignant neoplasm of the lymphoid tissue of the stomach, lung, mammary gland, kidney, liver, thyroid gland, thymus, and salivary gland. Intraoral MALT lymphoma is rare. We describe a case of MALT lymphoma arising in the buccal mucosa.
A 78-year-old man presented with swelling and indolent pain of the buccal mucosa on the left side. Clinical examination revealed a 40mm×45mm elastic soft, movable tumor in the left buccal mucosa. An excision with 10-mm surgical margins was performed to remove the lesion. Histopathologic evaluation of the tumor disclosed a lymphoma with MALT characteristics. However, there was no definitive evidence of MALT lymphoma. Further characterization by gene analysis led to the diagnosis of a MALT lymphoma. As of 11 months postoperatively, the patient remains free of recurrence.
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© Japanese Society of Oral and Maxillofacial Surgeons
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