Primary Glossodynia Well-Treated with Triple-Drug Combination: A Case Series

Abstract

Primary glossodynia is characterized by abnormal sensations such as tongue pain without pathological changes and is not fully understood. Primary glossodynia is reported to be associated with neurophathic pain. We describe the cases of 3 patients（2 males, 1 female, mean age 54.3 years, range 42-79 years） with primary glossodynia that was treated with the concomitant medication of pregabalin （50-300mg/day）, tramadol hydrochloride/acetaminophen tablets （37.5/325-150/1,300mg/day）, and powdered processed aconite roots （0.5-1.5mg/day）. This medication remarkably relieved the patientsʼ primary glossodynia and promoted health-reated quality of life of them. Significant adverse events did not occur in any of the cases.
This concomitant medication may be useful for the treatment of primary glossodynia.