Abstract
A 3-year-old girl complaining of epistaxis, in whom thrombocytopenia cyclically occurred at an interval of 20 to 25 days was reported. No antiplatelet antibody could be detected and the platelet aggregation study was normal. When platelet counts decreased, the percentage of macrothrombocytes increased and the life span of platelets was shortened. Treatment with corticosteroid and γ-globulin had no effect upon the cycle of thrombocytopenia. The cycle of thrombocytopenia disappeared after an episode of upper respiratory infection. Only two cases of cyclic thrombocytopenia in childhood have been reported in the literature that we could refer to.
