Abstract
We have done regular long-term continuous replacement therapy for 5 patients with hemophilia A and l patient with hemophilia B. Among 6 patients, 2 patients with hemophilia A and 1 patient with hemophilia B were regularly replaced before the age of 1 year old as soon as diagnosis was confirmed. Patients with hemophilia A received 25 IU/kg factor VIII three times a week, and the patient with hemophilia B received 25-50 IU/kg factor IX twice a week. They have been engaged in normal activities including sports participation without hemophilic arthropathy since receiving the regular long-term continuous replacement therapy. We suggest that the regular long-term continuous re-placement therapy improves quality of life in children with hemophilia A and B.
