Abstract
The Bone Marrow Transplantation Committee of the Society has conducted an annual registry of bone marrow transplantation in children in Japan since 1983. As of June 30, 1990, 732 patients had received stem-cell transplantation and were registered from 57 institutions. Among them, autologous bone marrow transplantation and autologous peripheral blood stem-cell transplantation were mainly performed in hematological malignancies or malignant solid tumors, and the former procedure was done in 192 children (88 alive) and the latter was done in 42 children (32 alive), respectively. Allogeneic or syngeneic bone marrow transplantation including fetal liver cell transplantation were given to 498 children, i.e. 133 cases of acute lymphocytic leukemia (65 alive), 129 cases of acute non-lymphocytic leukemia (85 alive), 39 cases of adult-type chronic myelocytic leukemia (29 alive), 6 cases of juvenile-type chronic myelocytic leukemia (4 alive), 19 cases of nonHodgkin lymphoma (11 alive), 11 cases of malignant solid tumors (4 alive), 99 cases of aplastic anemia (88 alive), 29 cases of severe combined immune deficiency (12 alive), and 33 other cases (28 alive). The total number of transplanted cases has increased from 540 to 732 during the past one year. The details are reported in this paper.