1991 Volume 5 Issue 2 Pages 162-166
An 11-year-old girl presented with a history of right cheek swelling. Histological findings of specimen excised from a tumor in the right maxillary sinus showed Burkitt's lymphoma. Computed tomography revealed her maxillary and ethmoidal sinuses in the right side to be filled with tumor, and a part of zygomatic bone to be destructed by invasion. An analysis of the surface marker of tumor cells revealed Ia+, B1+ B2-, CALLA- and SIgM+ (70%), indicating that cells of this tumor classified into B cell type. A chromosomal analysis of tumor cells showed 11q+, dup (12), lacking t (8 ; 14), t (2 ; 8), nor t (8 ; 22). She received systemic chemotherapy including high-dose (HD) CPM and HD MTX, attained a complete remission and received periodic consolidation therapies together with high-dose chemotherapy followed by autologous bone marrow transplantation (ABMT). She underwent no radiation therapy. She has presently remained in complete remission for abont 3 years, and is now followed as therapy-free. Further study is needed to clarify Burkitt's lymphoma without nonrandom translocation.