Abstract
We report an 8-year-old girl case with B-cell ALL (FAB L3) presenting exophthalmus and meningitis-like symptoms. There was a histological difference between cells in cerebrospinal fluid (CSF) and bone marrow (BM) cells. Repeated cytological examination of CSF could define the disease. We diagnoted her B-cell ALL by surface marker study. CT scan revealed a tumor in paranasal cavity, so we considered this case a leukemic stage of Burkitt lymphoma.