Intestinal Perforation in an Infant with Acute Myelocytic Leukemia

Abstract

We reported a case of intestinal perforation during remission induction therapy in a 3-year-old male with acute myelocytic leukemia. He complained of fever, petechiae and pain of right ear on onset. The patient was diagnosed as having AML (FAB, M2). He was treated with BHAC-AMP therapy, but unremitting high fever and watery diarrhea continued. He died of duodenal and jejunal perforation 40 days later. Autopsy revealed diffuse infiltration of leukemic cells in all laminae of intestine including the perforated lesions.