Abstract
We described two cases with hypereosinophilic syndrome. A 14-year-old girl (patient 1) was admitted because of elevation of transaminases (GOT, 515K-U ; GPT, 416K-U). Her total peripheral WBC count was 9, 900/μl (Eos ; 655 /μl). The eosinocyte counts gradually increased to the level of 10, 610/μl. Her pleural effusion and ascites were noted by chest X-P together with ultrasonography. In her ascites, many eosinocytes were shown cytologically. She was treated with prednisolone. Following this treatment, her clinical symptoms subsided. A 6-month-old boy (patient 2) was admitted with generalized rash and failure to thrive. On admission, his peripheral WBC count was 46, 140/μl (Eos ; 19, 380/μl). The liver scintigram using 99mTc-Sn colloid showed multiple defects and liver biopsy showed infiltration of eosinocytes. He was also treated with prednisolone, and then his clinical condition improved. Both ultrasonography and scintigraphy were useful for diagnosis and clinical evaluation, according to the experience of our cases.
