The Japanese Journal of Pediatric Hematology
Online ISSN : 1884-4723
Print ISSN : 0913-8706
ISSN-L : 0913-8706
A Case of Hepatic Angiome-Multinodulare with Spontaneous Regression
Toshihito NAGATAHideo MUGISHIMAHiroyuki HICHINOChikako USHIKAIMayumi TAKAMURAToshiaki SHIMADAMotoaki CHINTakashi SUZUKIKensuke HARADA
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1995 Volume 9 Issue 5 Pages 364-369

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Abstract
A case of hepatic angiome-multinodulare that regressed naturally is reported. The patient, a 2-month-old boy, had an abnormal hepaplastin test at the age of 1 month, including systolic murmur on the fourth left sternal border, hepatomegaly, and multiple cutaneous hemangiomas, suggesting hepatic angioma of the liver. Roentgenographic examinations demonstrated multinodular masses in the liver that were enhanced by intravenous contrast with computed tomography and magnetic resonance imaging (MRI). Echoscopic examination revealed blood flow and arteriovenous shunting in these masses, leading to a diagnosis of hepatic angiome-multinodulare. Low-dose prednisolone (0.5 mg/kg/day) was the only medication administered, because of the absence of heart failure. Regression of cutaneous angiomas and improvement of hepatomegaly were simultaneously observed at the age of 6 months, and MRI at 20 months was normal. The patient was considered to have hepatic angioma with natural regression. The clinical features of the disease entity and the problems of the therapeutic strategies are discussed.
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