The Japanese Journal of Pediatric Hematology
Online ISSN : 1884-4723
Print ISSN : 0913-8706
ISSN-L : 0913-8706
A Case of Cyclic Neutropenia with Oscillation of Two Blood Elements
Eri KONISHIYuka ISHIKOShunsuke UMEHARAMaki FUKUNAGATetsuo KAWAKAMIKen-ichi NISHIKAWA
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1995 Volume 9 Issue 6 Pages 436-439

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Abstract
We reported a three-month-old female infant with cyclic neutropenia. Not only neutrophils, but also reticulocytes had their own oscillations with this patient. She also showed chronic anemia. The period of neutropenia was between 26 to 27 days. The period of variation of reticulocytes was 10 to 16. The administration of recombinant granulocyte colony-stimulating factor twice a week increased the number of neutrophils. However, while she was suffering recurrent pharyngitis and coxitis, she needed the daily administration of rhG-CSF. The number of neutrophils was maintained above 1, 000/μl after the rhG-CSF treatment for 8 month. She did not have any serious infectious disease. The oscillation of reticulocytes continued during the rhG-CSF treatment.
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