Evaluation of Promotion of Appropriate Use of Meropenem by Ward Pharmacists and Antimicrobial Stewardship Team

Abstract

At Hiroshima City Hospital, the Antimicrobial Stewardship Team and ward pharmacists monitor cases where the administration of carbapenem antibiotics has been started, and make proposals to the doctor regarding the dose and selection of the antimicrobial agent, and so forth. In the present study, we verified the effectiveness of this approach. As a result, it is suggested that the de-escalation rate and the proposed prescription rate increased significantly, the antimicrobial agent use density / days of therapy value improved, and that this approach had certain utility. In contrast, there was no change in the administration days until de-escalation and the total administration period, and it was considered that the approach should be reviewed and further appropriate use of an antimicrobial agent should be promoted.