Antibacterial Activity of Antibiotics and Stability of Vitamins in Transfusion Mixed with Multi-Vitamin Infusion

Abstract

The antibacterial activity of antibiotics and the stability of vitamins in 8 transfusions mixed with antibiotics and multi-vitamin infusion (M. V. I.) were investigated and the following results were obtained. No change in appearance was observed 24 hr after the combination of antibiotics and M. V. I. pH was changed only when antibiotics and M. V. I. were mixed in 5 % Klinit. When mitomycin C was mixed in EL #3, Paremental A, Paremental B, Hicaliq #1 or Hicaliq #2, the lowering of antibacterial activity of mitomycin C was observed regardless of the presence of M. V. I. Vitamin A in Moriamin SN or Hicaliq #1 was decomposed by light. Vitamin B1 was decomposed with amino acid products such as Proteamin 12X and Moriamin SN, but this decomposition was decreased in the presence of rolitetracycline. Vitamin B₂ and Vitamin C were stable in the presence of transfusions and antibiotics.