Abstract
Comparative tests were made of 6 commercial products of 0.02% fluorometholone ophthalmic suspension in terms of the quantity, content, distribution of particle size, etc. by HPLC method. The results were as follows:
1) Some products showed smaller contents than the labelled amounts, although all samples had little deviation of content and quantity. 2) In all samples, the particles smaller than 32μm composed more than 90% of total. But in some products, a few particles larger than 32μm, produced by aggregation, were observed. 3) The number of shakings required for complete dispersion was larger than that given on observation.
