Abstract
Factor of the fundamental dosage form design were studied to minimize errors in tablet discrimination. The minimum difference in size which permits discrimination between tablets was determined by using round white tablets and sugar-coated tablets in 1-mm-graduated diameters. Analyses were also made as to colors, relationships between tastes and colors, and suitable tablet sizes for grasping and swallowing.
Obtained results showed that discrimination among the three preparations (2mg, 5mg, and 10mg tablets) is possible if their diameters differed by 2 to 3mm, but that there is a strong possibility of errors when the diameter differences range only from 0 to 1 mm. Analysis of other factors also showed clear results.
These results may suggest important clues to elucidation of tablet discriminatory features, fundamental factors in dosage form and package design.
