Japanese Journal of Hospital Pharmacy
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
Evaluation of Antiseptics in Antiseptic-resistant Strains of Methicillin-resistant Staphylococcus aureus
MASANORI SASATSUYUJI SHIRAIKEIICHI SHIMIZUNORIHISA NOGUCHIMEGUMI KONO
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1993 Volume 19 Issue 6 Pages 516-521

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Abstract
The effects of antiseptics used for disinfection of the hands and skin were evaluated in antiseptic-resistant strains of methicillin-resistant Staphylococcus aureus. After 105 cells of bacteria wee inoculated on the hands, they were disinfected with the antiseptics in accordance with their accompanying literature. Welpas®, ethanol for disinfection, and Isodine® sulution (10%) killed all strains including the high-level antiseptic-resistant strain. Hibiscrub® killed the sensitive strain, but could not completely kill the high-level resistant strain. Thirty minutes after the hands were disinfected with the antiseptics, 105 cells of bacteria were again inoculated on them. Welpas killed the sensitive strain, but could not kill the high-level resistant strain. Isodine solution (10%) killed all strains tested, but Hibiscrub could not fully kill the high-level resistant strain. These results clearly confirmed that if antiseptics are not properly chosen and used effectively, antiseptic-resistant strains may readily begin growing on the hands.
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© Japanese Society of Pharmaceutical Health Care and Sciences
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