Abstract
Adenosine triphosphate disodium (ATP) is sensitive to light, temperature and pH. Physicochemical stability of the commercial injectable ATP preparation containing a stabilizer was studied in various hydrogen-ion concentrations regulated with a buffer solution. A mixture of the ATP injection and a buffer solution of pH 2.0 to 13.0 was left to stand at 28°for 1 hour. Physical experiment was carried out by macroscopy and chemical expriment by thin layer chromatography. The injection showed no physicochemical change. It can be concluded that the commercial ATP injection (10mg/2ml) containing a stabilizer is stable in wide range of hydrogen-ion concentrations (pH 2 to 13).
