Abstract
Changes of injectable FOY, a newly developed agent for pancreatitis, on clinically expected combination with 68 injections were studied. The estimated change was studied in indirect method, change in appearance and fluctuation of pH in direct method, residue rate in UV method, and separation and identification by thin-layer chromatography. It is suggested in indirect method that injectable FOY is an agent with high tolerance, but a change was observed when combined with 38 of the 68 injection preparations in direct method, and residual potency was decreased in combination with 41 preparations in UV method. FOY is generally stable to light and temperature changes it is also stable in acidic buffer solutions but unstable in alkaline solutions. The drug was often found to be incompatible with alkaline injections and some cephalosporin antibiotics and synthetic penicillins.
