1979 Volume 5 Issue 1 Pages 54-57
Stability of hospital preparations of procaine hydrochloride injection is affected by various factors such as material of container, purity of ingredient, acidity and alkalinity of injection, and sterilizing method. Stability ofprocaine hydrochloride injection prepared at the authors' pharmacy was determined in terms of the decomposition constant which was calculated on the basis of residual procaine hydrochloride just after sterilization and after storage for 12 months at 25°. The date of expiration of the agent was determined on the date after 20 months (ie, the date when the rate of residual procaine hydrochloride decreased to 93%).