Japanese Journal of Hospital Pharmacy
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
Analysis of Injectable Preparations of Glycyrrhizin, Glycine and L-Cysteine
MASUMITSU TAKASUGIKAZUYOSHI MIYATAKAZUO MINAKUCHITAKABUMI UMEDAMICHIKO HUJITASHIGERU SHIMOMURASHINSUKE YAMASHITA
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1979 Volume 5 Issue 2 Pages 67-72

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Abstract
Analyis was carried out on 6 brands of commercial injectable preparations combining glycyrrhizin, glycine and L-cysteine. Inassay, glycyrrhizin was measured by spectrophotometry, glycine by titrimetry and L-cysteine by colorimetry. The particlesin size of 2-60μ were divided into 6 grades and their number was measured. Molecular structureof the preparations was studied by Laser Raman method.
Results are as follows: 1) There was nosignificant difference in contents of glycrrhizin and glycine among the brands. 2) Remarkable shortage of L-cysteine was observed in 2 brands. 3) Significant differences in particle size were observed among the brands. 4) One of the brands showed a large signal around 1000cm-1 in Laser Raman spectrum.
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© Japanese Society of Pharmaceutical Health Care and Sciences
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