Abstract
The serum level of antiepileptic drugs (diphenylhydantoin, phenobarbital, carbamazepine and primidone) was determined by modified Kupferberg's gas-liquid chromatography. Since the serum level of these drugs were found to be determined when they are within a therapeutic level, the test was made in children at the age of 3 to 17 years. The range of effective serum level of diphenylhydantoin was estimated at 5 to 10 μg/ml.
