Abstract
Recently there has been remarkable increase in the amount of antibiotics used for various infections. Various problems concerning drug-resistance or microbisme selectionné et substitué were studied in terms of frequency of use or combination of the antibiotics. The following results were obtained from the prescriptions written during June 1 to 30 of 1978, 1979 and 1980 at Miyazaki Medical College Hospital: 1) The ratio of antibiotic prescriptions to the total prescriptions was approximately 20-24%. 2) The descending order of the frequency of use by group of antibiotics was: cephalosporins, penicillins, aminoglycosides, tetracyclines, maclorides, others. The same tendency was seen in each of the three years. 3) Aminoglycosides were the most frequently combined antibiotics. 4) Among the departments, the department of surgery recorded the largest number of antibiotics (single and combined use), while the internal medicine had the largest number of prescriptions written.