A New Quantitative Filtration Apparatus to Evaluate Erythrocyte Deformability

Abstract

We have developed a quantitative filtration apparatus to evaluate erythrocyte deformability, using a precision metal filter which we developed. The test material is sucked into the filter through the action of decreasing negative pressure. The device automatically gives a liquid level (height)–time relation and a pressure–flow rate relation, similar to gravity-based filtration. Unlike the gravity-based system, the experimental performance of this system is very good and reproducible.