Abstract
1. By recording the integrated response of the glossopharyngeal nerve, the relative stimulating effectiveness of cations and anions on the frog tongue was measured.
2. Cations show stronger stimulating strength as compared with anions. The order of effectiveness is NH4>K>Cs>Na>Li for monovalent cations of 1/2 M and Ca>Sr>Mg>Ba for divalent cations of 1/64 M.
3. In the anion series no remarkable difference in the response magnitude was observed. Saccharin soluble, which is the monovalent organic sodium salt, shows nearly equal stimulating effectiveness to the monovalent inorganic sodium salts, while sodium glutamate gives smaller value.
