Abstract
Adrenal atrophy produced by adenohypophysectomy was the same in extent as that after total hypophysectomy. In adenohypophysectomized rats the corticosterone levels in the adrenal gland and blood plasma and the adrenal ascorbic acid concentration were decreased to the same levels as those found in totally hypophysectomized ones. Administration of epinephrine into adenohypophysectomized rats did not cause any increase in the corticosterone levels nor depletion in the adrenal ascorbic acid concentration.