Abstract
1. Effects of synthetic lysine vasopressin on the plasma concentration of FFA and in vitro oxygen consumption of tissues were studied in the rat.
2. The plasma FFA concentration decreased significantly following the injection of vasopressin, while the effect of oxytocin was less marked. Pre-treatment with vasopressin caused a significant suppression on norepinephrine, effect in increasing the plasma FFA concentration.
3. In vitro oxygen consumption of liver slices and hemidiaphragms was related to the medium concentration of palmitate.
4. In vitro release of FFA by epididymal fat pads was not affected by the addition of vasopressin. FFA releasing effect of norepinephrine was not influenced by the presence of vasopressin.
5. In vitro oxygen consumption of brown adipose tissue, liver and diaphragm was significantly reduced by the addition of vasopressin into the incubation medium, while that of white adipose tissue was not affected by vasopressin.
