Abstract
Epididymal fat pads of rats treated with lysine vasopressin released significantly less FFA and glycerol than the tissue of control rats. Vasopressin treatment effectively blocked the stimulatory effect of norepinephrine on adipose tissue lipolysis. Vasopressin, when given in vivo, was shown to be a potent inhibitor of hormone-sensitive lipase activity in white adipose tissue. On the other hand, appreciable change was not observed in the lipase activity of brown adipose tissue following vasopressin treatment.
Lipoprotein lipase activity of epididymal white fat as well as interscapular brown fat was not affected by both vasopressin and norepinephrine injections.
