Abstract
1. Ammonia content of sweat varied from 1mg. to 10.7mg. per 100cc. It was high in the initial stage of sweating when the secretion was scanty, and low when it became profuse. However, it did not increase usually when sweating gradually subsided by lowering room temperature.
2. Glutaminase I was found in human skin tissue but not in sweat.
3. Ammonia formation in human skin tissue was more remarkable in the presence of glutamine but not of glycine, alanine, glutamic acid, threonine, asparagine, tyrosine, histidine and urea. A large proportion of ammonia in sweat seems to be derived from glutamine.
